Two people who once shared everything now act as if they've never met. That is the heart of Abbie's short poem. The speaker looks back at a time when the closeness was total: they "bared our heart into one another with no secret left." Nothing was hidden, and nothing needed to be.
Then comes the turn. The sudden "Oh this life!" sounds like a sigh, part sorrow, part disbelief that things could change so completely. The title phrase, "best strangers," is the poem's sharpest moment. It twists a warm word, "best," into something painful. Being strangers after being soulmates is worse than never having known each other, because the memory of what was lost remains.
The mood is quiet and wistful, with a note of resignation. The speaker doesn't blame anyone or describe a fight. The poem simply states the distance, and that plain tone makes it feel more honest and more sad.