The speaker of "Misfit" describes a life of feeling out of place, and the poem's tight, clipped lines make that feeling hard to shake. Living "in black, / the color of oil" suggests something dark, heavy, and perhaps slick, hard to grip or wash away. The cry of "oy!" appears twice, once for being sick and once for being well. That repetition hints that the speaker's ups and downs sound equally weary, as if both states bring the same sigh.
The last lines are the most puzzling. The speaker is "found but missed" in every place, which suggests being noticed without really being known. The "letters from home / to home" loop back on themselves, so home seems to be both where the messages start and where they end, with the speaker stuck in between. Judging by the imagery, the mood is wry, lonely, and a little darkly humorous. It reads like someone who belongs nowhere, and who has learned to say so with a shrug and a groan.