The speaker says that office life has made them love staying home. It sounds like a simple, cozy preference: after a day of work, why not stay in? But the last line complicates that. Sitting up after supper, the speaker feels "as fat and full as a bell of plague," and the comparison turns the comfort into something heavier and a little sinister.
A bell of plague suggests a bell tolling for the dead, so the image brings in swollenness, sound, and doom all at once. The speaker is stuffed with food, round like a bell, perhaps weighed down and gloomy as well. The poem never says outright whether this is contentment or unease, and that ambiguity is what makes it interesting.
The mood is dry, wry, and slightly uneasy. Home looks like a refuge from work, yet the speaker seems bloated and stuck there. Judging by the tone, the love of home may be less a free choice than a reaction to the office, a retreat that leaves the speaker passive and heavy.