The title initials, «E.D.», suggest a nod to Emily Dickinson, and the poem does feel Dickinson-like: short, clipped, and full of odd turns. That is an inference from the initials and the style, not something the text confirms.
The speaker seems caught between saying no and saying yes. "No me to my yes" sounds like a self divided, one part refusing what another part wants. The next lines picture a mind that has pushed itself into thinking too learnedly, then slows down: "take time to think / whom I thank." The rhyme makes gratitude sound like a small, deliberate act rather than a reflex.
Then the tone shifts sharply. "Oh pill" brings in the body, maybe illness or medication, and "the cold red beef ages me" is jarring and physical. The image is raw, even a little grim. The mood is wry, guarded, and slightly uneasy: a mind doing its best to stay composed while the flesh reminds it of time passing.