Most people hear "heartbreak" and think of a relationship ending. Maria pushes back on that idea right away, saying it isn't just about love. She then builds a short list of other things that can hurt just as deeply: family, friends, and humiliation. Each one gets its own line, as if she is adding weight with every example.
The speaker seems to be someone who has been hurt in more than one way and feels that the usual definition leaves too much out. The final line widens the point, calling heartbreak "everything that comes with it." That phrase suggests pain tends to arrive in clusters, with embarrassment, loneliness, and family trouble all tangled together.
The mood is plain, honest, and a little weary. There is no decoration, no punctuation to speak of, and the repeated "heart break is" gives the poem a steady, almost matter-of-fact rhythm, like someone quietly setting the record straight.