Strangeweather starts with a startling claim: brain scans of people before and after COVID show a small loss of brain matter. From there the speaker makes a darkly funny leap. If everyone's brain shrank even a little, then everyone is a little dumber, and that includes the people running things and the people arguing online.
The poem then asks what advice suits a whole population in that state. The answer is simple and kind. Be careful about what you argue, fight, hate, hurt, and kill over. The list builds steadily, each verb heavier than the last. Then comes the plain request to be patient and forgiving, which the speaker calls timeless wisdom.
The ending turns the worry back on the speaker and on us. If our thinking is impaired, how would we ever know? The mood is wry and anxious, but also gentle. The poem uses a scary idea as a reason to go easy on each other, including ourselves.